malariagen_data.af1.Af1.plot_haplotype_clustering

Af1.plot_haplotype_clustering(region: str | Region | Mapping | List[str | Region | Mapping] | Tuple[str | Region | Mapping, ...], analysis: str = 'default', sample_sets: Sequence[str] | str | None = None, sample_query: str | None = None, cohort_size: int | None = None, random_seed: int = 42, color: str | None = None, symbol: str | None = None, linkage_method: Literal['single', 'complete', 'average', 'weighted', 'centroid', 'median', 'ward'] = 'single', count_sort: bool = True, distance_sort: bool = False, width: int | None = 1000, height: int | None = 500, show: bool = True, renderer: str | None = None, render_mode: Literal['auto', 'svg', 'webgl'] = 'auto', **kwargs) → Figure | None

Hierarchically cluster haplotypes in region and produce an interactive plot.

Parameters

regionstr or Region or Mapping or list of str or Region or Mapping or tuple of str or Region or Mapping

Region of the reference genome. Can be a contig name, region string (formatted like “{contig}:{start}-{end}”), or identifier of a genome feature such as a gene or transcript. Can also be a sequence (e.g., list) of regions.

analysisstr, optional, default: ‘default’

Which haplotype phasing analysis to use. See the phasing_analysis_ids property for available values.

sample_setssequence of str or str or None, optional

List of sample sets and/or releases. Can also be a single sample set or release.

sample_querystr or None, optional

A pandas query string to be evaluated against the sample metadata, to select samples to be included in the returned data.

cohort_sizeint or None, optional

Randomly down-sample to this value if the number of samples in the cohort is greater. Raise an error if the number of samples is less than this value.

random_seedint, optional, default: 42

Random seed used for reproducible down-sampling.

colorstr or None, optional

Name of variable to use to color the markers.

symbolstr or None, optional

Name of the variable to use to choose marker symbols.

linkage_method{‘single’, ‘complete’, ‘average’, ‘weighted’, ‘centroid’, ‘median’, ‘ward’}, optional, default: ‘single’

The linkage algorithm to use. See the Linkage Methods section of the scipy.cluster.hierarchy.linkage docs for full descriptions.

count_sortbool, optional, default: True

For each node n, the order (visually, from left-to-right) n’s two descendant links are plotted is determined by this parameter. If True, the child with the minimum number of original objects in its cluster is plotted first. Note distance_sort and count_sort cannot both be True.

distance_sortbool, optional, default: False

For each node n, the order (visually, from left-to-right) n’s two descendant links are plotted is determined by this parameter. If True, The child with the minimum distance between its direct descendants is plotted first.

widthint or None, optional, default: 1000

Plot width in pixels (px).

heightint or None, optional, default: 500

Plot height in pixels (px).

showbool, optional, default: True

If true, show the plot. If False, do not show the plot, but return the figure.

rendererstr or None, optional

The name of the renderer to use.

render_mode{‘auto’, ‘svg’, ‘webgl’}, optional, default: ‘auto’

The type of rendering backend to use. See also https://plotly.com/python/webgl-vs-svg/.

**kwargs

Passed through to px.scatter().

Returns

Figure or None

A plotly figure (only returned if show=False).