H12 / Burkina Faso An. coluzzii / Chromosome X / #2

This page describes a signal of selection found in the Burkina Faso An. coluzzii population using the H12 (Garud et al. 20XX) statistic.The focus of this signal is on chromosome arm X between positions 9,200,001 and 9,240,000. The evidence supporting this signal is weak (\Delta_{i} < 50 on one or both flanks).

Signal location. Blue markers show the values of the selection statistic. The dashed black line shows the fitted peak model. The shaded red area shows the focus of the selection signal. The shaded blue area shows the genomic region in linkage with the selection event. Use the mouse wheel or the controls at the top right of the plot to zoom in, and hover over genes to see gene names and descriptions.

Genes

Gene AGAP000519 (diacylglycerol kinase (ATP dependent)) overlaps the focal region.

No genes are within 50 kbp of the focal region.

Key to insecticide resistance candidate gene types: 1 metabolic; 2 target-site; 3 behavioural; 4 cuticular.

Overlapping signals

The following selection signals have a focus which overlaps with the focus of this signal.

Signal Focus Score (Left | Right)
H12 / Burkina Faso An. gambiae / Chromosome X / #2 X:9,180,001-9,260,000 394 (212 | 181)

Diagnostics

The information below provides some diagnostics from the Peak modelling algorithm.

Selection signal in context. @@TODO

Peak targetting. @@TODO

Peak fitting diagnostics. @@TODO

Model fit reports

Left flank, peak model:

[[Model]]
    Model(exponential)
[[Fit Statistics]]
    # function evals   = 43
    # data points      = 151
    # variables        = 3
    chi-square         = 0.030
    reduced chi-square = 0.000
    Akaike info crit   = -1281.281
    Bayesian info crit = -1272.229
[[Variables]]
    amplitude:   0.10157442 +/- 0.011534 (11.36%) (init= 0.5)
    decay:       0.15000003 +/- 0.028099 (18.73%) (init= 0.5)
    c:           0.01969838 +/- 0.001220 (6.20%) (init= 0.03)
    cap:         1 (fixed)
[[Correlations]] (unreported correlations are <  0.100)
    C(amplitude, decay)          = -0.581
    C(decay, c)                  = -0.229

Right flank, peak model:

[[Model]]
    Model(exponential)
[[Fit Statistics]]
    # function evals   = 47
    # data points      = 149
    # variables        = 3
    chi-square         = 0.016
    reduced chi-square = 0.000
    Akaike info crit   = -1353.806
    Bayesian info crit = -1344.794
[[Variables]]
    amplitude:   0.17412056 +/- 0.014558 (8.36%) (init= 0.5)
    decay:       0.15000000 +/- 3.02e-06 (0.00%) (init= 0.5)
    c:           0.02223599 +/- 0.000910 (4.09%) (init= 0.03)
    cap:         1 (fixed)
[[Correlations]] (unreported correlations are <  0.100)
    C(amplitude, decay)          =  0.782
    C(decay, c)                  =  0.231

Left flank, null model:

[[Model]]
    Model(constant)
[[Fit Statistics]]
    # function evals   = 6
    # data points      = 150
    # variables        = 1
    chi-square         = 0.039
    reduced chi-square = 0.000
    Akaike info crit   = -1236.375
    Bayesian info crit = -1233.364
[[Variables]]
    c:   0.02176614 +/- 0.001320 (6.07%) (init= 0.03)

Right flank, null model:

[[Model]]
    Model(constant)
[[Fit Statistics]]
    # function evals   = 6
    # data points      = 148
    # variables        = 1
    chi-square         = 0.035
    reduced chi-square = 0.000
    Akaike info crit   = -1232.942
    Bayesian info crit = -1229.945
[[Variables]]
    c:   0.02506406 +/- 0.001271 (5.07%) (init= 0.03)

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