Below is a table of insecticide resistance candidate genes with information about any overlapping signals of selection.
Please note that the list of genes has been manually curated and is likely to be incomplete. If you would like to suggest an addition, please leave a comment at the bottom of the page.
Please also note that the fact that there are any signals of selection overlapping or adjacent to a given gene does not prove that the gene is under selection. Each signal of selection may span a number of genes, and the true target of selection may be a different gene nearby. Similarly, if a gene does not have any overlapping or adjacent signals of selection, that does not prove it is selectively neutral. There are a number of technical reasons why a true signal of selection might not be detected.
| Gene | Name | Description | Location | No. signals (overlapping, adjacent) | Known locus |
|---|---|---|---|---|---|
| AGAP006028 | Rdl | Gaba-gated chloride channel subunit | 2L:25,363,652-25,434,556 | 13 (3, 10) | Rdl |
| AGAP004707 | para | Voltage-gated sodium channel | 2L:2,358,158-2,431,617 | 6 (5, 1) | Vgsc |
| AGAP000801 | GLURIIb | Ionotropic receptor gluriib | X:14,618,213-14,733,582 | 6 (4, 2) | |
| AGAP000803 | GLURIIa | Ionotropic receptor gluriia | X:14,738,910-14,744,472 | 5 (4, 1) | |
| AGAP012975 | Histamine-gated chloride channel subunit | X:4,334,265-4,335,087 | 5 (2, 3) | ||
| AGAP000798 | GLURIIc | Ionotropic receptor gluriic | X:14,600,998-14,612,133 | 5 (2, 3) | |
| AGAP006027 | Glutamate receptor, ionotropic , ampa | 2L:25,272,296-25,314,781 | 3 (3, 0) | ||
| AGAP007086 | Sodium channel protein | 2L:42,327,400-42,406,342 | 3 (3, 0) | ||
| AGAP001356 | ACE1 | Acetylcholinesterase | 2R:3,484,107-3,495,790 | 2 (2, 0) | Ace1 |
| AGAP006026 | 2L:25,174,728-25,195,703 | 2 (1, 1) | |||
| AGAP004021 | IR40a | Ionotropic receptor ir40a | 2R:47,922,057-47,924,574 | 1 (1, 0) | |
| AGAP004595 | GPRGBB2 | Putative gaba-b receptor 2 | 2R:58,230,212-58,238,127 | 1 (1, 0) | |
| AGAP010169 | 3R:49,859,628-49,870,902 | 1 (1, 0) | |||
| AGAP028032 | 3R:49,878,991-49,880,259 | 1 (1, 0) | |||
| AGAP004923 | IR64a | Ionotropic receptor ir64a | 2L:6,087,277-6,104,141 | 0 (0, 0) | |
| AGAP004969 | IR75d | Ionotropic receptor ir75d | 2L:7,301,876-7,303,528 | 0 (0, 0) | |
| AGAP005466 | IR75l | Ionotropic receptor ir75l | 2L:15,949,821-15,952,169 | 0 (0, 0) | |
| AGAP005527 | NMDAR3 | Ionotropic receptor nmdar3 | 2L:16,639,642-16,647,151 | 0 (0, 0) | |
| AGAP005599 | Ph-sensitive chloride channel | 2L:17,708,774-17,740,450 | 0 (0, 0) | ||
| AGAP006156 | GPRMGL1 | Putative metabotropic glutamate receptor 1 | 2L:27,308,590-27,323,533 | 0 (0, 0) | |
| AGAP007498 | IR75k | Ionotropic receptor ir75k | 2L:46,923,249-46,925,420 | 0 (0, 0) | |
| AGAP007707 | 2L:49,147,256-49,148,967 | 0 (0, 0) | |||
| AGAP001434 | Glutamate receptor, anionic | 2R:4,848,635-4,895,916 | 0 (0, 0) | ||
| AGAP001478 | NMDAR1 | Ionotropic receptor nmdar1 | 2R:5,390,305-5,394,755 | 0 (0, 0) | |
| AGAP001811 | IR75h.1 | Ionotropic receptor ir75h.1 | 2R:10,851,535-10,853,577 | 0 (0, 0) | |
| AGAP001913 | Histamine-gated chloride channel | 2R:12,021,329-12,023,879 | 0 (0, 0) | ||
| AGAP001990 | Histamine-gated chloride channel subunit | 2R:13,215,618-13,216,977 | 0 (0, 0) | ||
| AGAP002152 | alpha6 | Nicotinic acetylcholine receptor subunit alpha 6 | 2R:16,511,319-16,522,978 | 0 (0, 0) | |
| AGAP013363 | IR7i | Ionotropic receptor ir7i | 2R:26,793,376-26,795,314 | 0 (0, 0) | |
| AGAP013285 | IR7u | Ionotropic receptor ir7u | 2R:26,795,525-26,797,440 | 0 (0, 0) | |
| AGAP002797 | GLURIId | Ionotropic receptor gluriid | 2R:27,638,116-27,644,376 | 0 (0, 0) | |
| AGAP002904 | IR41a | Ionotropic receptor ir41a | 2R:29,130,386-29,133,257 | 0 (0, 0) | |
| AGAP002971 | alpha8 | Nicotinic acetylcholine receptor subunit alpha 8 | 2R:30,267,141-30,294,999 | 0 (0, 0) | |
| AGAP002972 | alpha2 | Nicotinic acetylcholine receptor subunit alpha 2 | 2R:30,325,462-30,371,076 | 0 (0, 0) | |
| AGAP002974 | alpha1 | Nicotinic acetylcholine receptor subunit alpha 1 | 2R:30,465,345-30,478,828 | 0 (0, 0) | |
| AGAP012951 | IR41c | Ionotropic receptor ir41c | 2R:39,202,960-39,205,176 | 0 (0, 0) | |
| AGAP003531 | IR41n | Ionotropic receptor ir41n | 2R:39,207,749-39,210,030 | 0 (0, 0) | |
| AGAP004432 | IR41t.1 | Ionotropic receptor ir41t.1 | 2R:55,959,989-55,962,321 | 0 (0, 0) | |
| AGAP012969 | IR41t.2 | Ionotropic receptor ir41t.2 | 2R:55,988,209-55,990,472 | 0 (0, 0) | |
| AGAP010411 | IR8a | Ionotropic receptor ir8a | 3L:2,867,458-2,870,025 | 0 (0, 0) | |
| AGAP010580 | 3L:6,474,643-6,477,162 | 0 (0, 0) | |||
| AGAP010694 | Glycine receptor alpha 1 subunit | 3L:8,638,234-8,655,749 | 0 (0, 0) | ||
| AGAP011349 | Gaba-gated chloride channel | 3L:21,584,469-21,612,837 | 0 (0, 0) | ||
| AGAP011968 | IR76b | Ionotropic receptor ir76b | 3L:35,687,053-35,690,662 | 0 (0, 0) | |
| AGAP007951 | IR68a | Ionotropic receptor ir68a | 3R:3,275,939-3,278,326 | 0 (0, 0) | |
| AGAP008511 | IR21a | Ionotropic receptor ir21a | 3R:11,468,382-11,471,590 | 0 (0, 0) | |
| AGAP008588 | alpha5 | Nicotinic acetylcholine receptor subunit alpha 5 | 3R:13,330,840-13,390,145 | 0 (0, 0) | |
| AGAP008759 | IR41b | Ionotropic receptor ir41b | 3R:17,137,047-17,139,240 | 0 (0, 0) | |
| AGAP009014 | IR31a | Ionotropic receptor ir31a | 3R:23,550,517-23,553,011 | 0 (0, 0) | |
| AGAP009158 | Guanylate cyclase | 3R:27,712,554-27,726,798 | 0 (0, 0) | ||
| AGAP009493 | alpha9 | Nicotinic acetylcholine receptor subunit alpha 9 | 3R:34,721,510-34,725,375 | 0 (0, 0) | |
| AGAP009514 | GPRGBB3 | Putative gaba-b receptor 3 | 3R:35,049,851-35,054,224 | 0 (0, 0) | |
| AGAP010057 | Nicotinic acetylcholine receptor, beta-2 subunit | 3R:48,486,273-48,488,026 | 0 (0, 0) | ||
| AGAP010059 | 3R:48,494,678-48,498,880 | 0 (0, 0) | |||
| AGAP010205 | 3R:50,696,700-50,698,440 | 0 (0, 0) | |||
| AGAP010272 | IR25a | Ionotropic receptor ir25a | 3R:51,917,004-51,920,501 | 0 (0, 0) | |
| AGAP010281 | GPRGBB1 | Putative gaba-b receptor 1 | 3R:51,987,227-52,014,754 | 0 (0, 0) | |
| AGAP012429 | NMDAR2 | Ionotropic receptor nmdar2 | UNKN:284,129-301,557 | 0 (0, 0) | |
| AGAP012447 | GLURIIe | Ionotropic receptor gluriie | UNKN:1,553,917-1,557,262 | 0 (0, 0) | |
| AGAP012581 | UNKN:17,437,539-17,438,715 | 0 (0, 0) | |||
| AGAP012872 | UNKN:35,447,753-35,448,867 | 0 (0, 0) | |||
| AGAP000038 | Gamma-aminobutyric acid receptor subunit beta | X:481,140-483,518 | 0 (0, 0) | ||
| AGAP000039 | Gamma-aminobutyric acid receptor subunit alpha | X:494,371-496,532 | 0 (0, 0) | ||
| AGAP000138 | alpha4 | Nicotinic acetylcholine receptor subunit alpha 4 | X:2,120,272-2,139,554 | 0 (0, 0) | |
| AGAP000256 | IR93a | Ionotropic receptor ir93a | X:4,900,441-4,905,540 | 0 (0, 0) | |
| AGAP000329 | alpha3 | Nicotinic acetylcholine receptor subunit alpha 3 | X:5,774,401-5,780,662 | 0 (0, 0) | |
| AGAP000466 | ACE2 | Acetylcholinesterase | X:8,049,063-8,054,326 | 0 (0, 0) | |
| AGAP000962 | alpha7 | Nicotinic acetylcholine receptor subunit alpha 7 | X:18,426,678-18,467,864 | 0 (0, 0) | |
| AGAP000966 | beta1 | Nicotinic acetylcholine receptor beta 1 | X:18,557,873-18,559,842 | 0 (0, 0) |