Cyp9k1 locus¶
This page provides information about the Cyp9k1 cytochrome P450 gene, a locus for which there is prior evidence of recent positive selection and/or an association with insecticide resistance in Anopheles mosquitoes.
The locus occurs on chromosome X from position 15,240,572 to 15,242,864.
The locus contains gene AGAP000818 (CYP9K1 - cytochrome P450).
References¶
- Main et al. (2015) Complex genome evolution in Anopheles coluzzii associated with increased insecticide usage in Mali
Selection signals¶
The table below lists signals of recent selection found in this study that are overlapping or within 50 kbp of this locus.
| Signal | Statistic | Population | Focus | Peak model  |
Max. percentile | Known locus |
|---|---|---|---|---|---|---|
| H12/BFM/X/1 | H12 | Burkina Faso An. coluzzii | X:15,100,000-15,300,000 | 1,267 | 100.0% | Cyp9k1 |
| XPEHH/BFS.GWA/X/1 | XPEHH | Burkina Faso An. gambiae | X:15,060,000-15,220,000 | 866 | 99.6% | Cyp9k1 |
| XPEHH/BFM.GWA/X/1 | XPEHH | Burkina Faso An. coluzzii | X:15,060,000-15,260,000 | 852 | 99.4% | Cyp9k1 |
| H12/BFS/X/1 | H12 | Burkina Faso An. gambiae | X:15,100,000-15,240,000 | 815 | 98.5% | Cyp9k1 |
| IHS/GNS/X/1 | IHS | Guinea An. gambiae | X:15,240,000-15,780,000 | 553 | 99.3% | Cyp9k1 |
| IHS/UGS/X/1 | IHS | Uganda An. gambiae | X:14,640,000-15,360,000 | 517 | 96.7% | Cyp9k1 |
| IHS/BFM/X/1 | IHS | Burkina Faso An. coluzzii | X:14,760,000-15,620,000 | 501 | 100.0% | Cyp9k1 |
| H12/UGS/X/1 | H12 | Uganda An. gambiae | X:15,160,000-15,480,000 | 348 | 94.9% | Cyp9k1 |
| XPEHH/UGS.CMS/X/1 | XPEHH | Uganda An. gambiae | X:15,240,000-15,460,000 | 284 | 99.9% | Cyp9k1 |
| XPEHH/UGS.BFS/X/1 | XPEHH | Uganda An. gambiae | X:14,960,000-15,320,000 | 204 | 89.8% | Cyp9k1 |