XPEHH/BFM.BFS/2/3

This page describes a signal of selection found in the Burkina Faso An. coluzzii population when compared with the Burkina Faso An. gambiae population using the XPEHH (Cite et al. 20XX) statistic.The focus of this signal is on chromosome arm 2L between positions 35,054,895 and 35,174,895. The evidence supporting this signal is moderate (\Delta_{i} >= 50 on both flanks).

Signal location. Blue markers show the values of the selection statistic. The dashed black line shows the fitted peak model. The shaded red area shows the focus of the selection signal. The shaded blue area shows the genomic region in linkage with the selection event. Use the mouse wheel or the controls at the top right of the plot to zoom in, and hover over genes to see gene names and descriptions.

Genes

Gene AGAP006634 (Semaphorin-2A) overlaps the focal region.

No genes are within 50 kbp of the focal region.

Key to insecticide resistance candidate gene types: 1 metabolic; 2 target-site; 3 behavioural; 4 cuticular.

Diagnostics

The information below provides some diagnostics from the Peak modelling algorithm.

Selection signal in context. @@TODO

Peak targetting. @@TODO

Peak fitting diagnostics. @@TODO

Model fit reports

Peak model:

[[Model]]
    Model(skewed_exponential_peak)
[[Fit Statistics]]
    # function evals   = 78
    # data points      = 806
    # variables        = 4
    chi-square         = 162.908
    reduced chi-square = 0.203
    Akaike info crit   = -1280.714
    Bayesian info crit = -1261.946
[[Variables]]
    center:      0 (fixed)
    amplitude:   1.26675997 +/- 0.102486 (8.09%) (init= 3)
    decay:       0.50591680 +/- 0.069117 (13.66%) (init= 0.5)
    skew:       -0.52934134 +/- 0.131995 (24.94%) (init= 0)
    baseline:    1.35465573 +/- 0.019291 (1.42%) (init= 1)
    ceiling:     100 (fixed)
    floor:       0 (fixed)
[[Correlations]] (unreported correlations are <  0.100)
    C(amplitude, decay)          = -0.602
    C(decay, baseline)           = -0.416
    C(decay, skew)               =  0.251

Null model:

[[Model]]
    Model(constant)
[[Fit Statistics]]
    # function evals   = 10
    # data points      = 805
    # variables        = 1
    chi-square         = 207.300
    reduced chi-square = 0.258
    Akaike info crit   = -1090.123
    Bayesian info crit = -1085.432
[[Variables]]
    c:   1.46504635 +/- 0.017896 (1.22%) (init= 1)

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