XPEHH/BFM.BFS/2/7

This page describes a signal of selection found in the Burkina Faso An. coluzzii population when compared with the Burkina Faso An. gambiae population using the XPEHH (Cite et al. 20XX) statistic.The focus of this signal is on chromosome arm 2L between positions 41,094,895 and 41,154,895. The evidence supporting this signal is weak (\Delta_{i} < 50 on one or both flanks).

Signal location. Blue markers show the values of the selection statistic. The dashed black line shows the fitted peak model. The shaded red area shows the focus of the selection signal. The shaded blue area shows the genomic region in linkage with the selection event. Use the mouse wheel or the controls at the top right of the plot to zoom in, and hover over genes to see gene names and descriptions.

Genes

Gene AGAP028463 overlaps the focal region.

The following 6 genes are within 50 kbp of the focal region: AGAP007028 (glucosyl/glucuronosyl transferases), AGAP007029 (glucosyl/glucuronosyl transferases), AGAP028734, AGAP028733, AGAP028735, AGAP007031 (Scabrous protein).

Key to insecticide resistance candidate gene types: 1 metabolic; 2 target-site; 3 behavioural; 4 cuticular.

Diagnostics

The information below provides some diagnostics from the Peak modelling algorithm.

Selection signal in context. @@TODO

Peak targetting. @@TODO

Peak fitting diagnostics. @@TODO

Model fit reports

Peak model:

[[Model]]
    Model(skewed_gaussian)
[[Fit Statistics]]
    # function evals   = 53
    # data points      = 820
    # variables        = 4
    chi-square         = 119.057
    reduced chi-square = 0.146
    Akaike info crit   = -1574.355
    Bayesian info crit = -1555.518
[[Variables]]
    center:      0 (fixed)
    amplitude:   0.98874289 +/- 0.094614 (9.57%) (init= 3)
    sigma:       0.27460608 +/- 0.035901 (13.07%) (init= 0.5)
    skew:       -0.99999547 +/- 0.167141 (16.71%) (init= 0)
    baseline:    1.24808211 +/- 0.014002 (1.12%) (init= 1)
    ceiling:     100 (fixed)
    floor:       0 (fixed)
[[Correlations]] (unreported correlations are <  0.100)
    C(sigma, skew)               =  0.558
    C(amplitude, sigma)          = -0.420
    C(sigma, baseline)           = -0.156
    C(amplitude, baseline)       = -0.106

Null model:

[[Model]]
    Model(constant)
[[Fit Statistics]]
    # function evals   = 9
    # data points      = 819
    # variables        = 1
    chi-square         = 134.741
    reduced chi-square = 0.165
    Akaike info crit   = -1476.075
    Bayesian info crit = -1471.367
[[Variables]]
    c:   1.28664618 +/- 0.014181 (1.10%) (init= 1)

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