XPEHH/GAS.GWA/3/2

This page describes a signal of selection found in the Gabon An. gambiae population when compared with the Guinea Bissau population using the XPEHH (Cite et al. 20XX) statistic.The focus of this signal is on chromosome arm 3R between positions 26,640,000 and 26,740,000. The evidence supporting this signal is weak (\Delta_{i} < 50 on one or both flanks).

Signal location. Blue markers show the values of the selection statistic. The dashed black line shows the fitted peak model. The shaded red area shows the focus of the selection signal. The shaded blue area shows the genomic region in linkage with the selection event. Use the mouse wheel or the controls at the top right of the plot to zoom in, and hover over genes to see gene names and descriptions.

Genes

No genes overlap the focal region.

No genes are within 50 kbp of the focal region.

Key to insecticide resistance candidate gene types: 1 metabolic; 2 target-site; 3 behavioural; 4 cuticular.

Overlapping selection signals

The following selection signals have a focus which overlaps with the focus of this signal.

Signal Statistic Population Focus Peak model \Delta_{i} Max. percentile Known locus
XPEHH/GAS.BFS/3/1 XPEHH Gabon An. gambiae 3R:26,640,000-26,800,000 220 99.5% nan

Diagnostics

The information below provides some diagnostics from the Peak modelling algorithm.

Selection signal in context. @@TODO

Peak targetting. @@TODO

Peak fitting diagnostics. @@TODO

Model fit reports

Peak model:

[[Model]]
    Model(skewed_gaussian)
[[Fit Statistics]]
    # function evals   = 48
    # data points      = 504
    # variables        = 4
    chi-square         = 131.041
    reduced chi-square = 0.262
    Akaike info crit   = -670.921
    Bayesian info crit = -654.030
[[Variables]]
    center:      0 (fixed)
    amplitude:   1.26788741 +/- 0.111512 (8.80%) (init= 3)
    sigma:       0.32611749 +/- 0.042349 (12.99%) (init= 0.5)
    skew:        0.99999996 +/- 0.160212 (16.02%) (init= 0)
    baseline:    1.97675695 +/- 0.025328 (1.28%) (init= 1)
    ceiling:     100 (fixed)
    floor:       0 (fixed)
[[Correlations]] (unreported correlations are <  0.100)
    C(sigma, skew)               = -0.606
    C(amplitude, sigma)          = -0.445
    C(sigma, baseline)           = -0.204
    C(amplitude, baseline)       = -0.168

Null model:

[[Model]]
    Model(constant)
[[Fit Statistics]]
    # function evals   = 11
    # data points      = 503
    # variables        = 1
    chi-square         = 174.843
    reduced chi-square = 0.348
    Akaike info crit   = -529.521
    Bayesian info crit = -525.300
[[Variables]]
    c:   2.09417386 +/- 0.026314 (1.26%) (init= 1)

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