XPEHH/GWA.BFS/3/1

This page describes a signal of selection found in the Guinea Bissau population when compared with the Burkina Faso An. gambiae population using the XPEHH (Cite et al. 20XX) statistic.The focus of this signal is on chromosome arm 3R between positions 660,000 and 700,000. The evidence supporting this signal is weak (\Delta_{i} < 50 on one or both flanks).

Signal location. Blue markers show the values of the selection statistic. The dashed black line shows the fitted peak model. The shaded red area shows the focus of the selection signal. The shaded blue area shows the genomic region in linkage with the selection event. Use the mouse wheel or the controls at the top right of the plot to zoom in, and hover over genes to see gene names and descriptions.

Genes

Gene AGAP007776 overlaps the focal region.

The following 3 genes are within 50 kbp of the focal region: AGAP007775 (ATP-dependent DNA helicase PIF1), AGAP007777, AGAP007778 (DNA-directed RNA polymerase, mitochondrial).

Key to insecticide resistance candidate gene types: 1 metabolic; 2 target-site; 3 behavioural; 4 cuticular.

Overlapping selection signals

The following selection signals have a focus which overlaps with the focus of this signal.

Signal Statistic Population Focus Peak model \Delta_{i} Max. percentile Known locus
IHS/GWA/3/1 IHS Guinea Bissau 3R:660,000-700,000 363 100.0% nan
XPEHH/GWA.UGS/3/1 XPEHH Guinea Bissau 3R:660,000-700,000 346 100.0% nan
XPEHH/GAS.BFS/3/2 XPEHH Gabon An. gambiae 3R:520,000-680,000 178 100.0% nan

Diagnostics

The information below provides some diagnostics from the Peak modelling algorithm.

Selection signal in context. @@TODO

Peak targetting. @@TODO

Peak fitting diagnostics. @@TODO

Model fit reports

Peak model:

[[Model]]
    Model(skewed_exponential_peak)
[[Fit Statistics]]
    # function evals   = 47
    # data points      = 464
    # variables        = 4
    chi-square         = 143.862
    reduced chi-square = 0.313
    Akaike info crit   = -535.357
    Bayesian info crit = -518.797
[[Variables]]
    center:      0 (fixed)
    amplitude:   3.51319647 +/- 0.211869 (6.03%) (init= 3)
    decay:       0.15000011 +/- 0.016287 (10.86%) (init= 0.5)
    skew:        0.99999945 +/- 0.114247 (11.42%) (init= 0)
    baseline:    1.57741703 +/- 0.028049 (1.78%) (init= 1)
    ceiling:     100 (fixed)
    floor:       0 (fixed)
[[Correlations]] (unreported correlations are <  0.100)
    C(amplitude, decay)          = -0.632
    C(decay, skew)               = -0.319
    C(decay, baseline)           = -0.226

Null model:

[[Model]]
    Model(constant)
[[Fit Statistics]]
    # function evals   = 11
    # data points      = 463
    # variables        = 1
    chi-square         = 285.250
    reduced chi-square = 0.617
    Akaike info crit   = -222.259
    Bayesian info crit = -218.121
[[Variables]]
    c:   1.75908972 +/- 0.036517 (2.08%) (init= 1)

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